SMOD: The smart wireless bio-photometer
SMOD delivers real time OD600 and temperature data so you can monitor suspension cell culture growth without any intervention, wherever you are.
Learn all about SMOD:
Features and …
Fully self-‐contained sealed unit with OD 600 and temperature sensors.
Simply chemically sterilized.
Smart induction charging allowing 35 uses.
Simply replace with SMOD solo units, retaining the charger for further use.
Simple and intuitive software to set up experiments to take measurements and view data.
Benefits
Save on expensive consumables and hours of time you usually use taking sample measurements.
No more removing from incubators and opening of cell culture flasks before harvest.
Perfect for anaerobes
The growth of the obligate anaerobe Clostridium difficile CCOS 941 was monitored using the SMOD data provided by Dr. G. Dasen, CCOS (Culture Collection of Switzerland AG) and ZHAW (Zurich University of Applied Sciences).
No more cell culture sampling at inconvenient times.
Optimised cell harvests and growth trend analysis.
Real time data wirelessly delivered to a lab PC and available on smart phones.
Technical Specifications
- Bluetooth – v2.0 or greater
- Supported Operating Systems – Windows 7, 8 or 10
- Supported Web Browsers – Internet Explorer 10+, Edge, Chrome or Firefox
- Diameter – 32.5mm (compatible with Erlenmeyer flasks with 34mm and greater circular openings)
- Fully sealed, ultrasonically welded polypropylene shell
- Inductions charged fully in around 4 hours on the proprietary induction charger base
- Up to 20 hours battery life on each full charge
- Multiple SMODs can be used for longer cultures
- Operate up to 7 units connected to a single PC and active at the same time
- Dedicated SMOD Software controls individual SMOD units
Winner: New Product Innovation Award at Basel Life Science Week / Miptec 2016
Applications and Technical Notes
SMOD is ideal for Anaerobic culture monitoring
The SMOD can be used to monitor the growth of anaerobic cultures. The growth of the obligate anaerobe Clostridium difficile CCOS 941 was monitored using the SMOD. Cells were grown at a constant temperature (370C) with agitation (200rpm) and the Optical Density (OD600) and temperature measured by the SMOD over 14 hours is graphed. (data provided by Dr. G. Dasen, CCOS – Culture Collection of Switzerland AG) and ZHAW – Zurich University of Applied Sciences).
SMOD is ideal in experiments to obtain the optimum induction time for protein expression and monitoring of the culture during protein expression.
Figure 1. Using the SMOD for protein expression in Escherichia coli. To demonstrate the use of the SMOD to monitor E. coli cultures during induction and expression of proteins. E. coli BLIM cells were inoculated into LB medium at an OD600 of 0.05 and the growth was monitored with the SMOD at a 15 minute time interval until an optical density of 0.5 was reached (Black arrows) . The culture was grown at constant temperature (370C) with agitation (200rpm). Then the cultures were removed from the incubator to cool to room temperature before induction. Once the temperature had dropped, protein expression was induced by adding Arabinose (concentration, Red arrows), and the cultures were returned to a 200C incubator and incubated for 10 hours at constant temperature (200C) with agitation (200rpm). The Optical Density (OD600) and temperature measured by the two SMODs during the experiment is graphed.
Documentation
To download a document right click on the link and then select “Save link as…” from the dropdown menu.
Technical Notes
Chemical Sterilisation of SMOD [LFNS-SMOD-0.1]
SMOD cell culture monitoring without manual intervention [LFNS-SMOD-0.2]
Chemical Sterilisation of SMOD (alternative) [LFNS-SMOD-0.3]
Effortless growth curves with the SMOD [LFNS-SMOD-0.4]
Anaerobic cell culture monitoring with the SMOD [LFNS-SMOD-0.5]
Monitoring slow growing cultures with the SMOD [LFNS-SMOD-0.6]
Recombinant protein expression in bacterial cultures using the SMOD [LFNS-SMOD-0.7]
Email Support
For further support please contact us at support@lifeonics.com.
Software Download
Before you download the SMOD Control Software we strongly recommend you read the Getting Started Guide.
Download SMOD Control Software
The current version of the SMOD Control Software can be used with up to 7 SMOD at any one time. An upcoming update will allow an unlimited number of SMODs to be used concurrently. Any SMODs you purchase will work with all versions of the software.
Distributors
Americas
North America – United BioChannels – jwhitmore@unitedbiochannels.com
Asia
India – Inkarp Insruments Pvt. Ltd – info@inkarp.co.in
Indonesia, Malaysia, Philippines, Singapore, Vietnam – Bio Laboratories Pte. Ltd. – biolab@biolab.com.sg
Japan – LIFEM KK – info@lifem.co.jp – website: lifem.co.jp
Korea – DI Biotech Ltd. – info@dibiotech.com
People’s Republic of China – AGP Bio Ltd. – in@apgbio.com – website: www.apgbio.com – tel: +86 21 5484 7570
Taiwan (ROC) – Han Gene Technologies Ltd. – hangene@hangene.com.tw
Thailand – Lab Expert Co. Ltd. – sales_instrument@labexpert.co.th
Australasia
Australia and Pacific Islands – John Morris Scientific – https://www.johnmorrisgroup.com/Contact-Us
New Zealand – Science Directions Ltd. – clive@sciencedirections.com
Europe
BENELUX – GC Biotech B.V – info@gcbiotech.com
Switzerland – Bucher Biotec A.G – http://www.bucher.ch/en/contact.html
United Kingdom – Thistle Scientific Ltd – info@thistlescientific.co.uk
Rest of Europe – Lifeonics Ltd. – ian.sanders@lifeonics.com
Denmark – Aage Christensen A/S – www.aagechristensen.dk
All Other Countries
All Other Countries – Lifeonics Ltd. – info@lifeonics.com